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GLRB (NM_000824) Human Recombinant Protein

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SKU
TP762425
Purified recombinant protein of Human glycine receptor, beta (GLRB), transcript variant 1, Met353-Lys471, with N-terminal His-ABP tag, expressed in E.coli, 50ug
Size:
50 ug
  $260.00
In Stock*
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Frequently Bought Together (1)

TA313930 Rabbit polyclonal anti-GLRB antibody
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region (Met353-Lys471) of GLRB
Tag N-His-ABP (Albumin-Binding Protein)
Predicted MW 28.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity >80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000815
Locus ID 2743
UniProt ID P48167
Cytogenetics 4q32.1
RefSeq Size 3076
RefSeq ORF 1491
Synonyms HKPX2
Summary This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2009
Protein Categories Intracellular Proteins, Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction
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Other "GLRB" proteins (2)
SKU Description Size Price
LC431266 Lyophilized GLRB HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY431266 Transient overexpression lysate of glycine receptor, beta (GLRB), transcript variant 3 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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