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Major Basic Protein (PRG2) (NM_002728) Human Recombinant Protein

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SKU
TP762104
Purified recombinant protein of Human proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) (PRG2),Leu17-End, with N-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Leu17-End) of PRG2
Tag N-His-ABP (Albumin-Binding Protein)
Predicted MW 23.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002719
Locus ID 5553
UniProt ID P13727
Cytogenetics 11q12.1
RefSeq Size 874
RefSeq ORF 666
Synonyms BMPG; MBP; MBP1; proMBP
Summary The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2014
Protein Categories Cytokines, Secreated Proteins
Protein Families Secreted Protein
Protein Pathways Asthma
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Other "Major Basic Protein" proteins (2)
SKU Description Size Price
LC400961 Lyophilized PRG2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400961 Transient overexpression lysate of proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) (PRG2) (as WB positive control) 100 ug
$436.00

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