OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

DDB2 (NM_000107) Human Recombinant Protein

Be the first to review this product
SKU
TP762063
Purified recombinant protein of Human damage-specific DNA binding protein 2, 48kDa (DDB2),Met1-Leu250, with N-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

Frequently Bought Together (1)

TA810712 DDB2 mouse monoclonal antibody,clone OTI2E12 100 ul
$447.00

Other products for "DDB2 or NM_000107"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Met1-Leu250) of DDB2
Tag N-His
Predicted MW 27.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000098
Locus ID 1643
UniProt ID Q92466
Cytogenetics 11p11.2
RefSeq Size 1870
RefSeq ORF 1281
Synonyms DDBB; UV-DDB2; XPE
Summary This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2014
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Nucleotide excision repair, p53 signaling pathway, Ubiquitin mediated proteolysis
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "DDB2" proteins (2)
SKU Description Size Price
LC424922 Lyophilized DDB2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY424922 Transient overexpression lysate of damage-specific DNA binding protein 2, 48kDa (DDB2) (as WB positive control) 100 ug
$436.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products