EXT1 (NM_000127) Human Recombinant Protein

SKU TP762062

Purified recombinant protein of Human exostosin 1 (EXT1),Glu205-Leu335, with N-terminal His-ABP tag, expressed in E. coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Glu205-Leu335) of EXT1
• Tag: N-His-ABP (Albumin-Binding Protein)
• Predicted MW: 30.2 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_000118
• Locus ID: 2131
• UniProt ID: Q16394
• Cytogenetics: 8q24.11
• RefSeq Size: 3376
• RefSeq ORF: 2238
• Synonyms: EXT; LGCR; LGS; TRPS2; TTV
• Summary: This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Heparan sulfate biosynthesis, Metabolic pathways