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NCOA2 (NM_006540) Human Recombinant Protein

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SKU
TP761992
Purified recombinant protein of Human nuclear receptor coactivator 2 (NCOA2),Met1-Ile280, with N-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Met1-Ile280)of NCOA2
Tag N-His
Predicted MW 31.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_006531
Locus ID 10499
UniProt ID Q15596
Cytogenetics 8q13.3
RefSeq Size 6157
RefSeq ORF 4392
Synonyms bHLHe75; GRIP1; KAT13C; NCoA-2; SRC2; TIF2
Summary The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2016
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome
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Other "NCOA2" proteins (2)
SKU Description Size Price
LC401959 Lyophilized NCOA2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401959 Transient overexpression lysate of nuclear receptor coactivator 2 (NCOA2) (as WB positive control) 100 ug
$665.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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