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TYK2 (NM_003331) Human Recombinant Protein

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SKU
TP761982
Purified recombinant protein of Human tyrosine kinase 2 (TYK2),Arg240-Val387, with N-terminal His-ABP tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Arg240-Val387)of TYK2
Tag N-His-ABP (Albumin-Binding Protein)
Predicted MW 31.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003322
Locus ID 7297
UniProt ID P29597
Cytogenetics 19p13.2
RefSeq Size 4262
RefSeq ORF 3561
Synonyms IMD35; JTK1
Summary This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35. provided by RefSeq, Sep 2020
Protein Categories Cytokines, Enzyme: Kinases, Immune system diseases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Jak-STAT signaling pathway
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Other "TYK2" proteins (1)
SKU Description Size Price
TP304351 Purified recombinant protein of Human tyrosine kinase 2 (TYK2), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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