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PNPLA1 (NM_173676) Human Recombinant Protein

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SKU
TP761955
Purified recombinant protein of Human patatin-like phospholipase domain containing 1 (PNPLA1), transcript variant 1,full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding full-length of PNPLA1
Tag N-GST and C-His
Predicted MW 75.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_775947
Locus ID 285848
UniProt ID Q8N8W4
Cytogenetics 6p21.31
RefSeq Size 2367
RefSeq ORF 1311
Synonyms ARCI10; dJ50J22.1
Summary The protein encoded by this gene belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jun 2012
Protein Categories Intracellular Proteins
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Other "PNPLA1" proteins (4)
SKU Description Size Price
LC406553 Lyophilized PNPLA1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC428981 Lyophilized PNPLA1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY406553 Transient overexpression lysate of patatin-like phospholipase domain containing 1 (PNPLA1), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY428981 Transient overexpression lysate of patatin-like phospholipase domain containing 1 (PNPLA1), transcript variant 3 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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