DUSP10 (NM_144729) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-GST and C-His |
| Predicted MW | 43.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_653330 |
| Locus ID | 11221 |
| UniProt ID | Q9Y6W6 |
| Cytogenetics | 1q41 |
| RefSeq Size | 1824 |
| RefSeq ORF | 1446 |
| Synonyms | MKP-5; MKP5 |
| Summary | Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2014 |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | MAPK signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "DUSP10" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC402107 | Lyophilized DUSP10 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC408157 | Lyophilized DUSP10 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY402107 | Transient overexpression lysate of dual specificity phosphatase 10 (DUSP10), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY408157 | Transient overexpression lysate of dual specificity phosphatase 10 (DUSP10), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP760997 | Purified recombinant protein of Human dual specificity phosphatase 10 (DUSP10), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.coli, 50ug | 50 ug |
$270.00
|
|
Citations
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