Desmin (DES) (NM_001927) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-GST and C-His |
| Predicted MW | 81.4 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001918 |
| Locus ID | 1674 |
| UniProt ID | P17661 |
| Cytogenetics | 2q35 |
| RefSeq Size | 2268 |
| RefSeq ORF | 1410 |
| Synonyms | CDCD3; CSM1; CSM2; LGMD1D; LGMD1E; LGMD2R |
| Summary | This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. provided by RefSeq, Jul 2008 |
| Protein Categories | Cardiovascular diseases, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Desmin" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC400713 | Lyophilized DES HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400713 | Transient overexpression lysate of desmin (DES) (as WB positive control) | 100 ug |
$436.00
|
|
| TP720562 | Recombinant protein of human desmin (DES) | 10 ug |
$340.00
|
|
| TP760253 | Recombinant protein of human desmin (DES), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug | 50 ug |
$270.00
|
|
Citations
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