Desmin (DES) Mouse Monoclonal Antibody [Clone ID: OTI4G1]

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SKU
TA502328
DES (Desmin ) mouse monoclonal antibody, clone OTI4G1 (formerly 4G1)
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI4G1
Application FC, IHC, WB
Recommended Dilution WB 1:200~500, IHC 1:150, FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human fragment corresponding to amino acids 104-391 of human DES (NP_001918) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.63 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 53.4 kDa
Gene Name desmin
Database Link
Background This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. provided by RefSeq, Jul 2008
Synonyms CDCD3; CSM1; CSM2; LGMD1D; LGMD1E; LGMD2R
Reference Data
Protein Categories Cardiovascular diseases, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
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Other "OTI4G1" antibodies (4)
SKU Description Size Price
CF502328 Carrier-free (BSA/glycerol-free) DES mouse monoclonal antibody, clone OTI4G1 (formerly 4G1) 100 ug
$620.00
TA502328AM DES (Desmin ) mouse monoclonal antibody, clone OTI4G1 (formerly 4G1), Biotinylated 100 ul
$509.00
TA502328BM DES (Desmin ) mouse monoclonal antibody, clone OTI4G1 (formerly 4G1), HRP conjugated 100 ul
$509.00
TA502328S DES (Desmin ) mouse monoclonal antibody, clone OTI4G1 (formerly 4G1) 30 ul
$200.00

file-alt Citations

Clinicopathological characteristics of primary peritoneal epithelioid mesothelioma of clear cell type: A case report
Du, Wei, Gao et al
Medicine (Baltimore) (2021) 100 (12), e25264 DOI: 10.1097/MD.0000000000025264
AI Summary: OriGene's PBS Wash buffer was used to wash tissue samples during immunohistochemical staining, aiding in the accurate diagnosis of primary peritoneal epithelioid mesothelioma of clear cell type in this case report.
Snippet: Rationale: Primary peritoneal epithelioid mesothelioma of clear cell type is an extremely rare en.;Endogenous peroxidase was blocked by DAKO EnVision FLEX peroxidase-blocking reagent for 10 minutes, and washed for 3 times in the PBS Wash buffer (Origene Technologies, Inc., Wuxi, China)
IHC
Transducer-like enhancer of split 1 (TLE1) as a novel biomarker for diagnosis of synovial sarcoma correlates with translocation t(X;18): a study of 155 cases in China
Li, Zhang, Wang et al
Int J Clin Exp Pathol (2019) 12 (1), 251-258
AI Summary: OriGene contributed to this study by providing the mouse polyclonal TLE1 antibody (used at 1:100 dilution) for immunohistochemical staining, enabling the assessment of TLE1 as a diagnostic biomarker for synovial sarcoma.
Snippet: Immunohistochemical staining was performed for CD117, CD56, cytokeratin AE1/AE3, EMA, CD99, BCL2, Vimentin, CD34, S100, Ki67, SMA and TLE1. Four-μm sections of formalin-fixed paraffin-embedded material were used according to standard laboratory procedures. Details of the antibodies used are given in Table 2. Immunohistochemical staining for TLE1 was performed following pressure cooker antigen retr...
IHC FISH
Clinicopathological analysis of epithelioid inflammatory myofibroblastic sarcoma
Du, Gao, Zhao et al
Oncol Lett (2018) 15 (6), 9317-9326 DOI: 10.3892/ol.2018.8530
Cited by 26
AI Summary: In this study, OriGene’s ALK (TA808063) and PD-L1 (TA591004) antibodies were used for immunohistochemical analysis to detect ALK and PD-L1 expression in tumor cells, aiding in the diagnosis and characterization of epithelioid inflammatory myofibroblastic sarcoma.
Showing 1-3 of 3 papers.
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