Desmin (DES) Mouse Monoclonal Antibody [Clone ID: OTI4G1]
SKU
CF502328
Carrier-free (BSA/glycerol-free) DES mouse monoclonal antibody, clone OTI4G1 (formerly 4G1)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI4G1 |
|---|---|
| Application | FC, IHC, WB |
| Recommended Dilution | WB 1:200~500, IHC 1:150, FLOW 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human fragment corresponding to amino acids 104-391 of human DES (NP_001918) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 53.4 kDa |
| Gene Name | desmin |
| Database Link | |
| Background | This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. provided by RefSeq, Jul 2008 |
| Synonyms | CDCD3; CSM1; CSM2; LGMD1D; LGMD1E; LGMD2R |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4G1" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA502328 | DES (Desmin ) mouse monoclonal antibody, clone OTI4G1 (formerly 4G1) | 100 ul |
$447.00
|
|
| TA502328AM | DES (Desmin ) mouse monoclonal antibody, clone OTI4G1 (formerly 4G1), Biotinylated | 100 ul |
$509.00
|
|
| TA502328BM | DES (Desmin ) mouse monoclonal antibody, clone OTI4G1 (formerly 4G1), HRP conjugated | 100 ul |
$509.00
|
|
| TA502328S | DES (Desmin ) mouse monoclonal antibody, clone OTI4G1 (formerly 4G1) | 30 ul |
$200.00
|
|
Citations
Clinicopathological characteristics of primary peritoneal epithelioid mesothelioma of clear cell type: A case report
Du, Wei, Gao et al
Medicine (Baltimore) (2021) 100 (12), e25264 DOI: 10.1097/MD.0000000000025264
Du, Wei, Gao et al
Medicine (Baltimore) (2021) 100 (12), e25264 DOI: 10.1097/MD.0000000000025264
AI Summary: OriGene's PBS Wash buffer was used to wash tissue samples during immunohistochemical staining, aiding in the accurate diagnosis of primary peritoneal epithelioid mesothelioma of clear cell type in this case report.
Snippet: Rationale: Primary peritoneal epithelioid mesothelioma of clear cell type is an extremely rare en.;Endogenous peroxidase was blocked by DAKO EnVision FLEX peroxidase-blocking reagent for 10 minutes, and washed for 3 times in the PBS Wash buffer (Origene Technologies, Inc., Wuxi, China)
Transducer-like enhancer of split 1 (TLE1) as a novel biomarker for diagnosis of synovial sarcoma correlates with translocation t(X;18): a study of 155 cases in China
Li, Zhang, Wang et al
Int J Clin Exp Pathol (2019) 12 (1), 251-258
Li, Zhang, Wang et al
Int J Clin Exp Pathol (2019) 12 (1), 251-258
AI Summary: OriGene contributed to this study by providing the mouse polyclonal TLE1 antibody (used at 1:100 dilution) for immunohistochemical staining, enabling the assessment of TLE1 as a diagnostic biomarker for synovial sarcoma.
Snippet: Immunohistochemical staining was performed for CD117, CD56, cytokeratin AE1/AE3, EMA, CD99, BCL2, Vimentin, CD34, S100, Ki67, SMA and TLE1. Four-μm sections of formalin-fixed paraffin-embedded material were used according to standard laboratory procedures. Details of the antibodies used are given in Table 2. Immunohistochemical staining for TLE1 was performed following pressure cooker antigen retr...
Clinicopathological analysis of epithelioid inflammatory myofibroblastic sarcoma
Du, Gao, Zhao et al
Oncol Lett (2018) 15 (6), 9317-9326 DOI: 10.3892/ol.2018.8530
Du, Gao, Zhao et al
Oncol Lett (2018) 15 (6), 9317-9326 DOI: 10.3892/ol.2018.8530
Cited by 26
Showing 1-3 of 3 papers.
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