TIMP1 (NM_003254) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-GST and C-His |
| Predicted MW | 48.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_003245 |
| Locus ID | 7076 |
| UniProt ID | P01033 |
| Cytogenetics | Xp11.3 |
| RefSeq Size | 931 |
| RefSeq ORF | 621 |
| Synonyms | CLGI; EPA; EPO; HCI; TIMP; TIMP-1 |
| Summary | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. provided by RefSeq, Jul 2008 |
| Protein Categories | Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "TIMP1" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC418808 | Lyophilized TIMP1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY418808 | Transient overexpression lysate of TIMP metallopeptidase inhibitor 1 (TIMP1) (as WB positive control) | 100 ug |
$436.00
|
|
| TP720383 | Recombinant protein of human TIMP metallopeptidase inhibitor 1 (TIMP1) | 10 ug |
$340.00
|
|
| TP723878 | Purified recombinant protein of Human TIMP metallopeptidase inhibitor 1 (TIMP1) | 10 ug |
$465.00
|
|
Citations
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