TIMP1 (NM_003254) Human Recombinant Protein

SKU
TP761577
Purified recombinant protein of Human TIMP metallopeptidase inhibitor 1 (TIMP1), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
  $270.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length TIMP1
Tag N-GST and C-His
Predicted MW 48.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003245
Locus ID 7076
UniProt ID P01033
Cytogenetics Xp11.3
RefSeq Size 931
RefSeq ORF 621
Synonyms CLGI; EPA; EPO; HCI; TIMP; TIMP-1
Summary This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. provided by RefSeq, Jul 2008
Protein Categories Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
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Other "TIMP1" proteins (4)
SKU Description Size Price
LC418808 Lyophilized TIMP1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418808 Transient overexpression lysate of TIMP metallopeptidase inhibitor 1 (TIMP1) (as WB positive control) 100 ug
$436.00
TP720383 Recombinant protein of human TIMP metallopeptidase inhibitor 1 (TIMP1) 10 ug
$340.00
TP723878 Purified recombinant protein of Human TIMP metallopeptidase inhibitor 1 (TIMP1) 10 ug
$465.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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