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PAGE4 (NM_007003) Human Recombinant Protein

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SKU
TP761394
Purified recombinant protein of Human P antigen family, member 4 (prostate associated) (PAGE4), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length PAGE4
Tag N-GST and C-His
Predicted MW 39 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_008934
Locus ID 9506
UniProt ID O60829
Cytogenetics Xp11.23
RefSeq Size 563
RefSeq ORF 306
Synonyms CT16.7; GAGE-9; GAGEC1; JM-27; JM27; PAGE-1; PAGE-4
Summary This gene is a member of the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in prostate and prostate cancer. It is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer. The protein encoded by this gene shares sequence similarity with other GAGE/PAGE proteins, and also belongs to a family of CT (cancer-testis) antigens. The protein may play a role in benign and malignant prostate diseases. A related pseudogene is located on chromosome 7. Alternate splicing results in multiple transcript variants. provided by RefSeq, Jan 2016
Protein Categories Intracellular Proteins
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Other "PAGE4" proteins (2)
SKU Description Size Price
LC416260 Lyophilized PAGE4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416260 Transient overexpression lysate of P antigen family, member 4 (prostate associated) (PAGE4) (as WB positive control) 100 ug
$436.00

file-alt Citations

The cancer/testis antigen prostate-associated gene 4 (PAGE4) is a highly intrinsically disordered protein
Zeng, He, Yang et al
J. Biol. Chem. (2011) 286 (16), 13985-94 DOI: 10.1074/jbc.M110.210765
Cited by 9
AI Summary: OriGene products, specifically the pCMV6-Entry and pCMV6-AC-GFP expression vectors, were used to facilitate the cloning and expression of PAGE4 protein in this study, enabling the characterization of PAGE4 as a highly intrinsically disordered protein.
Snippet: reading frame with C-terminal fusion of the DDK tag, pCMV6-Entry, and destination vector pCMV6-AC-GFP were purchased from Origene (Rockville, MD). ... (26) observed that the expression of lipoprotein lipase, a gene frequently deleted in prostate cancer, is down-regulated in
Showing 1-1 of 1 papers.
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