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ICAM4 (NM_001544) Human Recombinant Protein

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SKU
TP761371
Purified recombinant protein of Human intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length ICAM4
Tag N-GST and C-His
Predicted MW 55.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001535
Locus ID 3386
UniProt ID Q14773
Cytogenetics 19p13.2
RefSeq Size 1354
RefSeq ORF 813
Synonyms CD242; LW
Summary This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jul 2008
Protein Categories CD Markers, Intracellular Proteins, Membrane Proteins
Protein Families Secreted Protein, Transmembrane
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Other "ICAM4" proteins (8)
SKU Description Size Price
PH300636 ICAM4 MS Standard C13 and N15-labeled recombinant protein (NP_001034221) 10 ug
$3,360.00
LC411697 Lyophilized ICAM4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC419874 Lyophilized ICAM4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC422020 Lyophilized ICAM4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY411697 Transient overexpression lysate of intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY419874 Transient overexpression lysate of intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY422020 Transient overexpression lysate of intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP300636 Recombinant protein of human intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4), transcript variant 3, 20 µg 20 ug
$737.00

file-alt Citations

Natural IgG autoantibodies are abundant and ubiquitous in human sera, and their number is influenced by age, gender, and disease
Nagele, Han, Acharya et al
PLoS ONE (2013) 8 (4), e60726 DOI: 10.1371/journal.pone.0060726
Cited by 310
AI Summary: OriGene products TP300636 and TP315253 were used as antigen sources spotted onto nitrocellulose membranes to assess the binding profiles of IgG autoantibodies in human sera, enabling the study’s analysis of autoantibody abundance and diversity.
Snippet: TP300636 and TP315253, OriGene Technologies, Inc., Rockville, MD), were spotted onto a nitrocellulose membrane in 1 µl volumes. ... As shown in Figure 4B, although there are slight variations in individual band intensity from one blood withdrawal date to the next, the overall
FigureFigureFigure
Showing 1-1 of 1 papers.
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