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ELL (NM_006532) Human Recombinant Protein

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SKU
TP761317
Purified recombinant protein of Human elongation factor RNA polymerase II (ELL), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

Frequently Bought Together (1)

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length ELL
Tag N-GST and C-His
Predicted MW 94.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_006523
Locus ID 8178
UniProt ID P55199
Cytogenetics 19p13.11
RefSeq Size 4077
RefSeq ORF 1863
Synonyms C19orf17; ELL1; MEN; PPP1R68
Summary Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
Protein Families Transcription Factors
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Other "ELL" proteins (2)
SKU Description Size Price
LC416583 Lyophilized ELL HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416583 Transient overexpression lysate of elongation factor RNA polymerase II (ELL) (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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