PPAR alpha (PPARA) (NM_001001928) Human Recombinant Protein

CAT#: TP761203

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Purified recombinant protein of Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug


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USD 205.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length PPARA
Tag N-His
Predicted MW 52 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Reference Data
RefSeq NP_001001928
Locus ID 5465
Refseq Size 9965
Cytogenetics 22q13.31
Refseq ORF 1404
Synonyms hPPAR; NR1C1; PPAR; PPARalpha
Summary Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Adipocytokine signaling pathway, PPAR signaling pathway

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