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C1QC (NM_001114101) Human Recombinant Protein

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SKU
TP761200
Purified recombinant protein of Human complement component 1, q subcomponent, C chain (C1QC), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Frequently Bought Together (1)

TA324448 C1QC Antibody (Center)
400 ul
$645.00

Other products for "C1QC or NM_001114101"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length C1QC
Tag N-His
Predicted MW 22.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001107573
Locus ID 714
UniProt ID P02747
Cytogenetics 1p36.12
RefSeq Size 1205
RefSeq ORF 735
Synonyms C1Q-C; C1QG
Summary This gene encodes the C-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. provided by RefSeq, Dec 2016
Protein Categories Immune system diseases, Intracellular Proteins, Secreated Proteins
Protein Families Secreted Protein
Protein Pathways Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus
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Other "C1QC" proteins (6)
SKU Description Size Price
PH303832 C1QC MS Standard C13 and N15-labeled recombinant protein (NP_758957) 10 ug
$3,360.00
LC403541 Lyophilized C1QC HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC426451 Lyophilized C1QC HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403541 Transient overexpression lysate of complement component 1, q subcomponent, C chain (C1QC), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY426451 Transient overexpression lysate of complement component 1, q subcomponent, C chain (C1QC), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP303832 Recombinant protein of human complement component 1, q subcomponent, C chain (C1QC), transcript variant 2, 20 µg 20 ug
$867.00

file-alt Citations

Metaproteomic profiling reveals viral proteins and associated host proteomic alterations in glioblastoma
Gunasegaran, Krishnamurthy, Ahn et al
Sci Rep (2026)
AI Summary: In this study, OriGene products AFMID (TP317126), BCL2 (TP304498), and C1QC (TP761200) recombinant proteins were used to construct a spectral library for metaproteomic analysis of glioblastoma tissues, enabling the identification of viral and host proteomic alterations.
Snippet: The following recombinant proteins were used to construct the DDA recombinant 222 protein spectral library for this study: AADAT (R&D Systems, 7927-AT-010), AFMID 223 (OriGene Technologies, TP317126), BCL2 (OriGene, TP304498), C1QC (OriGene, 224 TP761200), CDX2 (Aviva Systems Biology, OPCD02118),
Improved FFPE Tissue Cancer-Associated Protein Detection using a Recombinant Protein Spectral Library (rPSL) DIA-MS Workflow
Ahn, Krishnamurthy, Alnakli et al
Research Square (2026)
AI Summary: OriGene products, specifically the recombinant proteins BTC (TP723036), C1QC (TP761200), and CPQ (TP760108), were used to construct the DDA recombinant protein spectral library (rPSL) that enabled improved detection of cancer-associated proteins in FFPE tissue using the DIA-MS workflow in this study.
Snippet: list of proteins used to construct the DDA recombinant protein spectral library (rPSL) for this study is provided in Table 1. The following recombinant proteins (listed by gene names) including BTC (OriGene Technologies, TP723036), C1QC (OriGene Technologies, TP761200), CDX2 (Aviva Systems Biology, OPCD02118), CEACAM5 (R&D systems, 4128-CM), CPQ (OriGene Technologies, TP760108), CXCL10 (IP10) (Or
Recombinant Protein Spectral Library (rPSL) DIA-MS method improves identification and quantification of low-abundance cancer-associated and kynurenine pathway proteins
Krishnamurthy, Gunasegaran, Paul-Heng et al
Commun Chem (2025) 8 (1), 141 DOI: 10.1038/s42004-025-01531-0
Cited by 6
AI Summary: OriGene products, including recombinant proteins BTC (TP723036), C1QC (TP761200), and CPQ (TP760108), were used to generate the recombinant protein spectral library (rPSL), which enhanced the identification and quantification of low-abundance cancer-associated proteins in the study.
Snippet: appsilber et al69, and dried using the SpeedVac Vacuum concentrator (Thermo Fisher Scientific). Recombinant proteins The following recombinant proteins including AADAT (R&D systems, 7927-AT-010), BTC OriGene Technologies, TP723036), C1QC (OriGene Technologies, TP761200), CDX2 (Aviva Systems Biology, OPCD02118), CEACAM5 (R&D systems, 4128-CM), CPQ (OriGene Technologies, TP760108), CXCL10 (IP10) (Or
FigureFigureFigure
Recombinant Protein Spectral Library (rPSL) DIA-MS Method Improves Identification and Quantification of Low-Abundance Cancer-Associated and Kynurenine Pathway Proteins
Krishnamurthy, Gunasegaran, Paul-Heng et al
Research Square (2024)
Snippet: The following recombinant proteins including AADAT (R&D systems, 7927- AT-010), BTC OriGene Technologies, TP723036), C1QC (OriGene Technologies, TP761200), CDX2 (Aviva Systems Biology, OPCD02118), CEACAM5 (R&D systems, 4128-CM), CPQ (OriGene Technologies, TP760108), CXCL10 (IP10) (OriGene Technologies, TP723726), CXCL12 (R&D systems, 350-NS), CXCL8 (IL8) (OriGene Technologies, TP721122),
TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration
Zhong, Sheng, Wang et al
Immunity (2023) 56 (8), 1794-1808.e8 DOI: 10.1016/j.immuni.2023.06.016
Cited by 165
AI Summary: OriGene products C1qa (TP761199) and C1qc (TP761200) were used as recombinant proteins in ELISA assays to investigate the binding interactions between TREM2 and complement components in this study.
Snippet: Solid-phase binding was performed in a 96-well plate using enzyme-linked immunosorbent assay (ELISA). C1q (Complement Technology, A099), C1qa (OriGene, TP761199), C1qb (SinoBiological, China, 10941-H08B), C1qc (OriGene, TP761200), C1 (Complement Technology, A098), C2 (Complement Technology, A112), or C3 (EMD Millipore, 204885) in PBS was immobilized onto plate wells overnight with 100 mL per well
Use of a Recombinant Biomarker Protein DDA Library Increases DIA Coverage of Low Abundance Plasma Proteins
Ahn, Kamath, Mohamedali et al
J Proteome Res (2021)
Cited by 25
AI Summary: In this study, OriGene products TIMP2 (TP723886) and TNFRSF1A (TP723870) were used as recombinant proteins to construct a spectral library, which enabled improved detection of low abundance cancer-associated plasma proteins by mass spectrometry.
Snippet: Credible detection and quantification of low abundance proteins from human blood plasma is a major challenge in precision medicine biomarker discovery when using mass spectrometry (MS). In this pro...;TIMP2 (TP723886) andTNFRSF1A (TP723870) were purchased from OriGeneTechnologies, CEACAM5 (4128-CM), CST3 (1196-PI),
Showing 1-6 of 6 papers.
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