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Granzyme B (GZMB) (NM_004131) Human Recombinant Protein

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SKU
TP761150
Purified recombinant protein of Human granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Frequently Bought Together (1)

TA505930 GZMB mouse monoclonal antibody,clone OTI4E6 100 ul
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length GZMB
Tag N-GST and C-His
Predicted MW 51.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_004122
Locus ID 3002
UniProt ID P10144
Cytogenetics 14q12
RefSeq Size 941
RefSeq ORF 741
Synonyms C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT
Summary This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. provided by RefSeq, Sep 2016
Protein Categories ADC Targets, Cytokines, Enzyme: Peptidases, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Protease
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus
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Other "Granzyme B" proteins (3)
SKU Description Size Price
LC401332 Lyophilized GZMB HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401332 Transient overexpression lysate of granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB) (as WB positive control) 100 ug
$436.00
TP306495 Purified recombinant protein of Human granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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