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HIC2 (NM_015094) Human Recombinant Protein

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SKU
TP760963
Purified recombinant protein of Human hypermethylated in cancer 2 (HIC2), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Frequently Bought Together (1)

TA329406 Rabbit Polyclonal anti-HIC2 antibody
100 ul
$585.00

Other products for "HIC2 or NM_015094"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length HIC2
Tag N-His
Predicted MW 66 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_055909
Locus ID 23119
UniProt ID Q96JB3
Cytogenetics 22q11.21
RefSeq Size 6794
RefSeq ORF 1845
Synonyms HRG22; ZBTB30; ZNF907
Summary Transcriptional repressor.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Transcription Factors
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Documents
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Other "HIC2" proteins (2)
SKU Description Size Price
LC414786 Lyophilized HIC2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY414786 Transient overexpression lysate of hypermethylated in cancer 2 (HIC2) (as WB positive control) 100 ug
$436.00

file-alt Citations

Haploinsufficiency in PTPN2 leads to early-onset systemic autoimmunity from Evans syndrome to lupus
Jeanpierre, Cognard, Tusseau et al
J Exp Med (2024) 221 (9) DOI: 10.1084/jem.20232337
Cited by 32
AI Summary: OriGene’s PTPN2 full sequence plasmid (isoform TC48, NM_002828) was used in this study to investigate the functional consequences of PTPN2 mutations associated with early-onset systemic autoimmunity.
Snippet: Plasmid containing PTPN2 full sequence (isoform TC48, NM_002828) was obtained from OriGene and subcloned in lentiviral vector p197 pRRLSIN-MND-IRES2-ZsGreen
FigureFigureFigure
Functional dissection of human cardiac enhancers and noncoding de novo variants in congenital heart disease
Xiao, Zhang, Morton et al
Nat Genet (2024)
Cited by 55
AI Summary: OriGene products contributed to this study by providing expression plasmids for the human proteins SRF (TP308596), TBX20 (TP762422), HIC2 (TP760963), SOX9 (TP308944), and GATA4 (TP310945), which were used to investigate the effects of noncoding variants on cardiac gene regulation.
Snippet: human proteins used in this study included SMAD2 (Abcam, ab85329), SRF (OriGene, TP308596), TBX20 (OriGene, TP762422), HIC2 (OriGene, TP760963), SOX9 (OriGene, TP308944) and GATA4 (OriGene, TP310945). The percentage of probe shifted was calculated by quantifying the free and shifted probe intensities using Fiji and then calculating
Showing 1-2 of 2 papers.
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