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PFKFB1 (NM_002625) Human Recombinant Protein

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SKU
TP760672
Purified recombinant protein of Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

Frequently Bought Together (1)

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length PFKFB1
Tag N-His
Predicted MW 54.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002616
Locus ID 5207
UniProt ID P16118
Cytogenetics Xp11.21
RefSeq Size 1756
RefSeq ORF 1413
Synonyms F6PK; HL2K; PFRX
Summary This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Nov 2012
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Fructose and mannose metabolism
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Other "PFKFB1" proteins (4)
SKU Description Size Price
PH324599 PFKFB1 MS Standard C13 and N15-labeled recombinant protein (NP_002616) 10 ug
$3,360.00
LC419200 Lyophilized PFKFB1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419200 Transient overexpression lysate of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1) (as WB positive control) 100 ug
$665.00
TP324599 Recombinant protein of human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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