SP1 (NM_138473) Human Recombinant Protein

CAT#: TP760592

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Purified recombinant protein of Human Sp1 transcription factor (SP1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug


 Product Datasheet for 'TP760592'

 Cited in 1 publication.

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USD 205.00


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    • 50 ug


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Specifications

Product Data
Description Purified recombinant protein of Human Sp1 transcription factor (SP1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length SP1
Tag N-His
Predicted MW 80.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris,8M Urea,pH8.0.
Reference Data
RefSeq NP_612482
Locus ID 6667
Refseq Size 7667
Cytogenetics 12q13.13
Refseq ORF 2355
Synonyms Sp1 transcription factor; specificity protein 1
Summary The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
Protein Pathways Huntington's disease, TGF-beta signaling pathway

Citations (1)

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