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DUSP11 (NM_003584) Human Recombinant Protein

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SKU
TP760533
Purified recombinant protein of Human dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) (DUSP11), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length DUSP11
Tag N-His
Predicted MW 38.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003575
Locus ID 8446
UniProt ID O75319
Cytogenetics 2p13.1
RefSeq Size 1639
RefSeq ORF 990
Synonyms PIR1
Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. provided by RefSeq, Sep 2008
Protein Categories Cytokines, Intracellular Proteins
Protein Families Druggable Genome, Phosphatase
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Other "DUSP11" proteins (2)
SKU Description Size Price
LC401192 Lyophilized DUSP11 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401192 Transient overexpression lysate of dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) (DUSP11) (as WB positive control) 100 ug
$436.00

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