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NEDD8 (NM_006156) Human Recombinant Protein

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SKU
TP760489
Purified recombinant protein of Human neural precursor cell expressed, developmentally down-regulated 8 (NEDD8), with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

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TA314245 Rabbit polyclonal anti-NEDD8 antibody
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length NEDD8
Tag N-His
Predicted MW 8.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_006147
Locus ID 4738
UniProt ID Q15843
Cytogenetics 14q12
RefSeq Size 625
RefSeq ORF 243
Synonyms NEDD-8
Summary Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Documents
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Other "NEDD8" proteins (1)
SKU Description Size Price
TP720985 Purified recombinant protein of Human neural precursor cell expressed, developmentally down-regulated 8 (NEDD8) 10 ug
$145.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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