RIP (RIPK1) (NM_003804) Human Recombinant Protein

CAT#: TP760433

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Purified recombinant protein of Human receptor (TNFRSF)-interacting serine-threonine kinase 1 (RIPK1), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

  View other "RIPK1" proteins (2)

USD 261.00

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    • 50 ug

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Frequently bought together (1)
RIPK1 (RIP) mouse monoclonal antibody, clone OTI2A8 (formerly 2A8)
    • 100 ul

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Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length RIPK1
Tag N-His
Predicted MW 75.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_003795
Locus ID 8737
UniProt ID Q13546, A0A024QZU0
Cytogenetics 6p25.2
Refseq Size 3864
Refseq ORF 2013
Synonyms AIEFL; IMD57; RIP; RIP-1; RIP1
Summary This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Apoptosis, Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway


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