Dectin 1 (CLEC7A) (NM_197950) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-His |
| Predicted MW | 19 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_922941 |
| Locus ID | 64581 |
| UniProt ID | Q9BXN2 |
| Cytogenetics | 12p13.2 |
| RefSeq Size | 2355 |
| RefSeq ORF | 504 |
| Synonyms | BGR; CANDF4; CD369; CLECSF12; DECTIN1; SCARE2 |
| Summary | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. provided by RefSeq, Jul 2008 |
| Protein Categories | CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Dectin 1" proteins (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC405148 | Lyophilized CLEC7A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC405151 | Lyophilized CLEC7A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC405152 | Lyophilized CLEC7A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY405148 | Transient overexpression lysate of C-type lectin domain family 7, member A (CLEC7A), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY405151 | Transient overexpression lysate of C-type lectin domain family 7, member A (CLEC7A), transcript variant 5 (as WB positive control) | 100 ug |
$436.00
|
|
| LY405152 | Transient overexpression lysate of C-type lectin domain family 7, member A (CLEC7A), transcript variant 6 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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