ATF 4(ATF4) (NM_001675) Human Recombinant Protein

CAT#: TP760367

Purified recombinant protein of Human activating transcription factor 4 (tax-responsive enhancer element B67) (ATF4), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

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 Product Datasheet for 'TP760367'

USD 199.00


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    • 50 ug

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Product Data
Description Purified recombinant protein of Human activating transcription factor 4 (tax-responsive enhancer element B67) (ATF4), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Species Human
Expression Host E.Coli
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC222709, encoding human full-length ATF4
Tag N-His
Predicted MW 38.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001666
Locus ID 468
Refseq Size 2022
Cytogenetics 22q13.1
Refseq ORF 1053
Synonyms CREB-2; CREB2; TAXREB67; TXREB
Summary This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011].
Protein Families
Protein Pathways
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