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PSMA1 (NM_002786) Human Recombinant Protein

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SKU
TP760007
Recombinant protein of human proteasome (prosome, macropain) subunit, alpha type, 1 (PSMA1), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length PSMA1
Tag N-His
Predicted MW 28.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002777
Locus ID 5682
UniProt ID P25786
Cytogenetics 11p15.2
RefSeq Size 1281
RefSeq ORF 789
Synonyms HC2; HEL-S-275; NU; PROS30
Summary The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.provided by RefSeq, Jan 2009
Protein Categories Enzyme: Peptidases, Intracellular Proteins
Protein Families Druggable Genome, Protease
Protein Pathways Proteasome
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Documents
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Other "PSMA1" proteins (2)
SKU Description Size Price
LC419114 Lyophilized PSMA1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419114 Transient overexpression lysate of proteasome (prosome, macropain) subunit, alpha type, 1 (PSMA1), transcript variant 2 (as WB positive control) 100 ug
$436.00

file-alt Citations

Ultrasensitive detection of cancer biomarkers by nickel-based isolation of polydisperse extracellular vesicles from blood
Notarangelo, Zucal, Modelska et al
EBioMedicine (2019) 43, 114-126 DOI: 10.1016/j.ebiom.2019.04.039
AI Summary: OriGene’s recombinant his-tagged PSMA protein (NM_002786) was used in this study to generate a standard curve for quantifying prostate-specific membrane antigen (PSMA) levels in extracellular vesicle samples.
Snippet: … We used a biotinylated antibody against human PSMA (Cusabio, CSB-PA018865LD01HU) and a recombinant his-tagged PSMA (Origene, {"type":"entrez-nucleotide","attrs":{"text":"NM_002786","term_id":"221316713","term_text":"NM_002786"}}NM_002786 [/nuccore/NM_002786]) for a standard curve quantification. 2.13. …We used a biotinylated antibody against human PSMA (Cusabio, CSB-PA018865LD01HU) and a recombinant his-tagged PSMA (Origene, {"type":"entrez-nucleotide","attrs":{"text":"NM_002786","term_id":"221316713","term_text":"NM_002786"}}NM_002786 [/nuccore/NM_002786]) for a standard curve quantification. 2.13. REVERSE TRAN;;Skip to article;We used a biotinylated antibody against human PSMA (Cusabio, CSB-PA018865LD01HU) and a recombinant his-tagged PSMA (Origene, NM_002786) for a standard curve quantification
Showing 1-1 of 1 papers.
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