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CYP1A1 (NM_000499) Human Recombinant Protein

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SKU
TP750202
Purified recombinant protein of Human cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), full-length, with N-terminal Myc-ddk tag, expressed in E.coli, 50ug
Size:
50 ug
  $260.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding full-length of CYP1A1
Tag Myc-DDK
Predicted MW 60.9kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 85% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 500 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000490
Locus ID 1543
UniProt ID P04798
Cytogenetics 15q24.1
RefSeq Size 2608
RefSeq ORF 1536
Synonyms AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX
Summary This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jan 2016
Protein Categories Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, P450, Transmembrane
Protein Pathways Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tryptophan metabolism
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Other "CYP1A1" proteins (4)
SKU Description Size Price
PH305760 CYP1A1 MS Standard C13 and N15-labeled recombinant protein (NP_000490) 10 ug
$3,360.00
LC400170 Lyophilized CYP1A1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400170 Transient overexpression lysate of cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) (as WB positive control) 100 ug
$436.00
TP305760 Recombinant protein of human cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), 20 µg 20 ug
$737.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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