Vitronectin (VTN) (NM_000638) Human Recombinant Protein

SKU
TP750077
Purified recombinant protein of Human vitronectin (VTN), esidues 62-478aa, Tag free, expressed in E.coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region (Vla62-Leu478) of VTN
Tag Tag Free
Predicted MW 47.5 kDa
Concentration >0.05 µg/µL as determined by Bradford protein assay method.
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH 7.4, 8% trehalose
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000629
Locus ID 7448
UniProt ID P04004
Cytogenetics 17q11.2
RefSeq Size 1678
RefSeq ORF 1434
Synonyms V75; VN; VNT
Summary The protein encoded by this gene functions in part as an adhesive glycoprotein. Differential expression of this protein can promote either cell adhesion or migration as it links cells to the extracellular matrix through a variety of ligands. These ligands include integrins, plasminogen activator inhibitor-1, and urokinase plasminogen activator receptor. This secreted protein can be present in the plasma as a monomer or dimer and forms a multimer in the extracellular matrix of several tissues. This protein also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpin serine protease inhibitors. This protein can also promote extracellular matrix degradation and thus plays a role in tumorigenesis. It is involved in a variety of other biological processes such as the regulation of the coagulation pathway, wound healing, and tissue remodeling. The heparin-binding domain of this protein give it anti-microbial properties. It is also a lipid binding protein that forms a principal component of high density lipoprotein. provided by RefSeq, Aug 2020
Protein Categories Growth Factors, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways ECM-receptor interaction, Focal adhesion
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Other "Vitronectin" proteins (6)
SKU Description Size Price
PH302929 VTN MS Standard C13 and N15-labeled recombinant protein (NP_000629) 10 ug
$3,360.00
LC400215 Lyophilized VTN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400215 Transient overexpression lysate of vitronectin (VTN) (as WB positive control) 100 ug
$436.00
TP302929 Recombinant protein of human vitronectin (VTN), 20 µg 20 ug
$867.00
TP720655 Purified recombinant protein of Human vitronectin (VTN) 10 ug
$160.00
TP790066 Purified recombinant protein of Human vitronectin (VTN), esidues 20-478aa, with N-terminal HIS tag, secretory expressed in HEK293, 50ug 50 ug
$540.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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