IL2 (NM_000586) Human Recombinant Protein

CAT#: TP750020

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Purified recombinant protein of Homo sapiens Interleukin 2 (IL-2) produced in E. coli.



  View other "IL2" proteins (8)

USD 425.00


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Size
    • 100 ug


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Specifications

Product Data
Description Purified recombinant protein of Homo sapiens Interleukin 2 (IL-2) produced in E. coli.
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding the region (Ala21-Thr153) of Homo sapiens Interleukin 2 and the molecule has serine substituted for cysteine at amino acid position 125
Tag Tag Free
Predicted MW 15.5 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a sterile MiliQ-water containing Trehalose, pH7.0.
Endotoxin < 0.1 EU per 1 µg of the protein by the LAL
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000577
Locus ID 3558
Refseq Size 822
Cytogenetics 4q27
Refseq ORF 459
Synonyms IL-2; lymphokine; TCGF
Summary The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus

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IL2 mouse monoclonal antibody,clone OTI2C9
    • 100 ul

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