FGF10 (NM_004465) Human Recombinant Protein

CAT#: TP750011

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Recombinant protein of human Fibroblast Growth Factor-10 (FGF10) produced in E. coli.


 Product Datasheet for 'TP750011'

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USD 411.00


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    • 100 ug


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Specifications

Product Data
Description Recombinant protein of human Fibroblast Growth Factor-10 (FGF10) produced in E. coli.
Species Human
Expression Host E. coli
Tag Tag Free
Predicted MW 19.3 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a sterile solution containing 20 mM phosphate buffer, pH7.4.
Bioactivity Determined by the dose-dependant stimulation of 4MBr-5 cells. ED50 for this effect is typically 14 - 21 ng/ml.
Endotoxin < 0.1 EU per 1 µg of the protein by the LAL
Reference Data
RefSeq NP_004456
Locus ID 2255
Refseq Size 627
Cytogenetics 5p12
Refseq ORF 624
Synonyms fibroblast growth factor 10; keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria
Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008]
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein, Transcription Factors, Transmembrane
Protein Pathways MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

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