CTLA4 Human Recombinant Protein
$565.00
4 Weeks*
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Product Data | |
Species | Human |
---|---|
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Protein Sequence
CTLA-4(Gln36-Ser161)+hFc(Glu99-Ala330)
|
Tag | C-Human Fc |
Predicted MW | 39.6 kDa |
Purity | > 95% |
Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
Reconstitution Method | Reconstitute with deionized water |
Preparation | Affinity purification |
Recommended Dilution | Flow Cyt |
Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
Stability | 12 months from date of despatch |
Shipping | Ambient |
Reference Data | |
Locus ID | 1493 |
UniProt ID | P16410 |
Summary | This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
Protein Families | Flow Cyt |
Protein Pathways | Autoimmune thyroid disease, Cell adhesion molecules (CAMs), T cell receptor signaling pathway |
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FAQs |
SDS |
Recombinant Protein Resources |
SKU | Description | Size | Price | |
---|---|---|---|---|
LC417438 | CTLA4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$134.00
|
|
LC421970 | CTLA4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$134.00
|
|
LY417438 | Transient overexpression lysate of cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1 | 100 ug |
$436.00
|
|
LY421970 | Transient overexpression lysate of cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 2 | 100 ug |
$436.00
|
|
TP700216 | Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells | 20 ug |
$867.00
|
|
TP700217 | Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1, with C-terminal human Fc and his tags, expressed in human cells | 20 ug |
$867.00
|
|
TP721230 | Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1 | 10 ug |
$155.00
|
|
TP723874 | Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1 | 10 ug |
$185.00
|
|
TP723940 | Human CTLA-4 Protein, mFc-His Tag | 100 ug |
$620.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.