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CTLA4 Human Recombinant Protein

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SKU
TP724014
Recombinant human CTLA-4 protein with C-terminal human Fc tag
Size:
100 ug
  $905.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (1)

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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
CTLA-4(Lys36-Asp161) hFc(Glu99-Ala330)
Tag C-Human Fc Tag
Predicted MW The protein has a predicted molecular mass of 39.6 kDa after removal of the signal peptide.The apparent molecular mass of CTLA4-hFc is approximately 40-55 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Recommended Dilution Flow Cyt
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 1493
UniProt ID P16410
Synonyms CTLA4;CD152
Summary This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Protein Categories ADC Targets, Allergies and autoimmune diseases, CD Markers, Diabetes, Intracellular Proteins, Membrane Proteins, Nervous system Diseases
Protein Families Flow Cyt
Protein Pathways Autoimmune thyroid disease, Cell adhesion molecules (CAMs), T cell receptor signaling pathway
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Other "CTLA4" proteins (9)
SKU Description Size Price
LC417438 Lyophilized CTLA4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC421970 Lyophilized CTLA4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY417438 Transient overexpression lysate of cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY421970 Transient overexpression lysate of cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP700216 Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells 20 ug
$900.00
TP700217 Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1, with C-terminal human Fc and his tags, expressed in human cells 20 ug
$900.00
TP721230 Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1 10 ug
$160.00
TP723874 Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1 10 ug
$185.00
TP723940 Recombinant human CTLA-4 protein with C-terminal mouse Fc and 6×His tag 100 ug
$905.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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