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IL5 Human Recombinant Protein

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SKU
TP723988
Recombinant Human IL5 protein with C-terminal 6×His tag
Size:
100 ug
  $825.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (1)

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Other products for "IL5"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
IL5(Ile20-Ser134) 6×His tag
Tag C-6×His Tag
Predicted MW The protein has a predicted molecular mass of 13.94 kDa after removal of the signal peptide.The apparent molecular mass of IL5-His is approximately 15-25 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 3567
UniProt ID P05113
Synonyms IL-5;TRF;Interleukin-5;EDF
Summary This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Protein Categories Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Jak-STAT signaling pathway, T cell receptor signaling pathway
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Other "IL5" proteins (5)
SKU Description Size Price
LC424470 Lyophilized IL5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY424470 Transient overexpression lysate of interleukin 5 (colony-stimulating factor, eosinophil) (IL5) (as WB positive control) 100 ug
$436.00
TP701241 Purified recombinant protein of Human interleukin 5 (colony-stimulating factor, eosinophil) (IL5), with C-terminal His tag, secretory expressed in HEK293 cells, 50ug 50 ug
$900.00
TP721241 Purified recombinant protein of Human interleukin 5 (colony-stimulating factor, eosinophil) (IL5) 10 ug
$340.00
TP750229 Purified recombinant protein of Human interleukin 5 (colony-stimulating factor, eosinophil) (IL5), Ile20-End, 50 µg 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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