GCSF Receptor (CSF3R) Human Recombinant Protein

SKU
TP723986
Recombinant human CD114 protein with C-terminal 6×His tag
  $825.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
CD114(Glu25-Glu622) 6×His tag
Tag C-6×His Tag
Predicted MW The protein has a predicted molecular mass of 67.5 kDa after removal of the signal peptide.The apparent molecular mass of CD114-His is approximately 100-110 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 1441
UniProt ID Q99062
Synonyms CSF3R;CD114;GCSFR
Summary The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.
Protein Categories Cancer: Haematopoietic and Lymphoid, CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer
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Other "GCSF Receptor" proteins (6)
SKU Description Size Price
LC403523 Lyophilized CSF3R HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC406926 Lyophilized CSF3R HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC424528 Lyophilized CSF3R HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403523 Transient overexpression lysate of colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 3 (as WB positive control) 100 ug
$665.00
LY406926 Transient overexpression lysate of colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY424528 Transient overexpression lysate of colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 1 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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