GCSF Receptor (CSF3R) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-6×His Tag |
| Predicted MW | The protein has a predicted molecular mass of 67.5 kDa after removal of the signal peptide.The apparent molecular mass of CD114-His is approximately 100-110 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 1441 |
| UniProt ID | Q99062 |
| Synonyms | CSF3R;CD114;GCSFR |
| Summary | The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. |
| Protein Categories | Cancer: Haematopoietic and Lymphoid, CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "GCSF Receptor" proteins (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC403523 | Lyophilized CSF3R HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC406926 | Lyophilized CSF3R HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC424528 | Lyophilized CSF3R HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403523 | Transient overexpression lysate of colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 3 (as WB positive control) | 100 ug |
$665.00
|
|
| LY406926 | Transient overexpression lysate of colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY424528 | Transient overexpression lysate of colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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