TNFRSF4 Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Human Fc and 6×His Tag |
| Predicted MW | The protein has a predicted molecular mass of 47.2 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | Flow Cyt |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 7293 |
| UniProt ID | P43489 |
| Synonyms | TNFRSF4;OX40;CD134;OX40L receptor;ACT35;TXGP1L |
| Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4 T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
| Protein Categories | CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Flow Cyt |
| Protein Pathways | Cytokine-cytokine receptor interaction |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "TNFRSF4" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH311253 | TNFRSF4 MS Standard C13 and N15-labeled recombinant protein (NP_003318) | 10 ug |
$3,360.00
|
|
| LC418746 | Lyophilized TNFRSF4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY418746 | Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 4 (TNFRSF4) (as WB positive control) | 100 ug |
$436.00
|
|
| TP311253 | Recombinant protein of human tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), 20 µg | 20 ug |
$737.00
|
|
| TP700284 | Purified recombinant protein of human tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), with C-terminal DDK/His tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.