TNFSF18 Human Recombinant Protein

SKU TP723943

Human GITR Ligand Protein, mFc-His tag

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  mFc（Pro99-Lys330）+GITR Ligand（Gln50-Ser177）+6×His
• Tag: N-Mouse Fc and C-6×His
• Predicted MW: 46-53 kDa
• Purity: > 95%
• Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
• Reconstitution Method: Reconstitute with deionized water
• Preparation: Affinity purification
• Storage: Store the lyophilized protein at -20°C.; After reconstitution, store the protein at -80°C for 12 months.; Avoid repeated freezing and thawing.
• Stability: 12 months from date of despatch
• Shipping: Ambient

Reference Data

• Locus ID: 8995
• UniProt ID: Q9UNG2
• Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction