CD137 (TNFRSF9) Human Recombinant Protein

SKU TP723934

Human 4-1BB Protein, mFc-His Tag

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  41BB（Leu24-Gln186）+mFc（Pro99-Lys330）+6×His
• Tag: C-Mouse Fc and 6×His
• Predicted MW: 54-60 kDa
• Purity: > 95%
• Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
• Reconstitution Method: Reconstitute with deionized water
• Preparation: Affinity purification
• Recommended Dilution: Flow Cyt
• Storage: Store the lyophilized protein at -20°C.; After reconstitution, store the protein at -80°C for 12 months.; Avoid repeated freezing and thawing.
• Stability: 12 months from date of despatch
• Shipping: Ambient

Reference Data

• Locus ID: 3604
• UniProt ID: Q07011
• Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
• Protein Families: Flow Cyt
• Protein Pathways: Cytokine-cytokine receptor interaction