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CD137 (TNFRSF9) Human Recombinant Protein

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SKU
TP723934
Recombinant human 4-1BB protein with C-terminal mouse Fc and 6×His tag
Size:
100 ug
  $905.00
4 Weeks*
Bulk/Customize

Other products for "CD137"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
41BB(Leu24-Gln186) mFc(Pro99-Lys330) 6×His
Tag C-Mouse Fc and 6×His Tag
Predicted MW The protein has a predicted molecular mass of 54-60 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Recommended Dilution Flow Cyt
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 3604
UniProt ID Q07011
Synonyms TNFRSF9;4-1BB;CD137;CDw137;ILA
Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Protein Categories CD Markers, Intracellular Proteins, Membrane Proteins
Protein Families Flow Cyt
Protein Pathways Cytokine-cytokine receptor interaction
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Resources
Other "CD137" proteins (7)
SKU Description Size Price
TP700283 Purified recombinant protein of human tumor necrosis factor receptor superfamily, member 9 (TNFRSF9), with C-terminal DDK/His tag, expressed in human cells, 20 µg 20 ug
$900.00
TP721369 Human 4-1BB/TNFRSF9 Protein (C-Fc) 25 ug
$300.00
TP721370 Human 4-1BB/TNFRSF9 Protein (C-Fc-Avi) 25 ug
$300.00
TP721371 Biotinylated Human 4-1BB/TNFRSF9 Protein (C-Fc-Avi) 25 ug
$430.00
TP721372 PE Conjugated Human 4-1BB/TNFRSF9 Protein (C-Fc) 25 ug
$430.00
TP721373 APC Conjugated Human 4-1BB/TNFRSF9 Protein (C-Fc) 25 ug
$430.00
TP724029 Recombinant human 4-1BB protein with C-terminal 6×His tag 100 ug
$905.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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