CD47 Human Recombinant Protein

SKU
TP723931
Recombinant human CD47 protein with C-terminal mouse Fc and 6×His tag
  $795.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
CD47(Gln19-Glu141) CD47(Val198-Ala207) CD47(Ser257-Gly268) mFc(Pro99-Lys330) 6×His tag
Tag C-Mouse Fc and 6×His Tag
Predicted MW The protein has a predicted molecular mass of 60 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Recommended Dilution ELISA
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 961
UniProt ID Q08722
Synonyms CD47;MER6;IAP;OA3
Summary Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
Protein Categories ADC Targets, CAR-T Targets, CD Markers, Intracellular Proteins, Membrane Proteins
Protein Families ELISA
Protein Pathways ECM-receptor interaction
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Other "CD47" proteins (9)
SKU Description Size Price
LC404792 Lyophilized CD47 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC419754 Lyophilized CD47 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY404792 Transient overexpression lysate of CD47 molecule (CD47), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY419754 Transient overexpression lysate of CD47 molecule (CD47), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP700196 Purified recombinant protein of Homo sapiens CD47 molecule (CD47), residues 19-141aa, with C-terminal Fc tag, expressed in HEK293 cells. 20 ug
$900.00
TP700197 Purified recombinant protein of Homo sapiens CD47 molecule (CD47), residues 19-141aa, with C-terminal DDK/His tag, expressed in HEK293 cells. 20 ug
$900.00
TP710231 Purified recombinant protein of Human CD47 molecule (CD47), transcript variant 1, residues 19-141aa, with C-terminal DDK tag, expressed in sf9, 20ug 20 ug
$540.00
TP720635 Purified recombinant protein of Human CD47 molecule (CD47), transcript variant 2 10 ug
$235.00
TP720959 Purified recombinant protein of Human CD47 molecule (CD47), transcript variant 2 10 ug
$340.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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