Ctla4 (NM_009843) Mouse Recombinant Protein

CAT#: TP723873

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Purified recombinant protein of Mouse cytotoxic T-lymphocyte-associated protein 4 (Ctla4)


Product Datasheet for 'TP723873'


USD 150.00


Availability*
5 Days

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Mouse cytotoxic T-lymphocyte-associated protein 4 (Ctla4)
Species Mouse
Expression Host CHO
Expression cDNA Clone or AA Sequence Mouse CTLA-4, the region of Ala37-Phe162, from gene Accession# NM_009843
Tag Fc chimera
Predicted MW 41 kDa
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity >95%, as determined by Coomassie stained SDS-PAGE
Buffer 1 x PBS
Bioactivity The ED50 is 70 - 350 ng/ml, corresponding to a specific activity of 0.28-1.4 x 104 units/mg, determined by the dose dependent inhibition of IL-2 production induced by 0.5 µg/ml of CD80 on Jurkat cells
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Reference Data
RefSeq NP_033973
Locus ID 12477
Refseq Size 1933
Cytogenetics 1 30.58 cM
Refseq ORF 669
Synonyms Cd152; Ctla-4; Ly-56
Summary This gene is a member of the immunoglobulin superfamily, and encodes a protein that functions as a negative regulator of T-cell responses. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]

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