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CD40L (CD40LG) (NM_000074) Human Recombinant Protein

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SKU
TP723872
Purified recombinant protein of Human CD40 ligand (CD40LG / TNFSF5)
Size:
10 ug
  $255.00
5 Days*
Bulk/Customize

Frequently Bought Together (1)

TA600027 CD40L mouse monoclonal capture antibody, validated for ELISA and Luminex assays
100 ug
$458.00

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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Human CD40L, the region of Glu108-Leu261, from gene Accession# NM_000074.2
Tag N-His
Predicted MW 19 kDa
Concentration lot specific
Purity >95%, as determined by Coomassie stained SDS-PAGE
Buffer 1 x PBS
Bioactivity Human CD40L induced the proliferation of human B cells in the presence of IL-4 in a dose-dependent manner. The ED50 for this effect is 6 – 36 ng/mL.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000065
Locus ID 959
UniProt ID P29965
Cytogenetics Xq26.3
RefSeq Size 1834
RefSeq ORF 783
Synonyms CD40L; CD154; gp39; hCD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP
Summary The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. provided by RefSeq, Jul 2008
Protein Categories CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Cytokine-cytokine receptor interaction, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Viral myocarditis
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Other "CD40L" proteins (3)
SKU Description Size Price
LC400020 Lyophilized CD40LG HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400020 Transient overexpression lysate of CD40 ligand (CD40LG) (as WB positive control) 100 ug
$436.00
TP720010 Recombinant protein of human CD40 ligand (CD40LG), the domain of Met113-Leu261 10 ug
$190.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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