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CD40L (CD40LG) (NM_000074) Human Recombinant Protein

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SKU
TP720010
Recombinant protein of human CD40 ligand (CD40LG), the domain of Met113-Leu261
Size:
10 ug 500 ug 50 ug 1 mg
  $190.00
5 Days*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Met113-Leu261
Tag Tag Free
Predicted MW 16.2 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM PB, 200mM NaCl, 0.1mM EDTA, pH 7.0.
Bioactivity ED50 is 5-10 ng/ml as determined by the dose-dependent stimulation of IL-12 & IL-8 induction by PMB (Peripheral Mononuclear) cells.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_000065
Locus ID 959
UniProt ID P29965
Cytogenetics Xq26.3
Synonyms CD40L; CD154; gp39; hCD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP
Summary The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. provided by RefSeq, Jul 2008
Protein Categories CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Cytokine-cytokine receptor interaction, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Viral myocarditis
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Other "CD40L" proteins (3)
SKU Description Size Price
LC400020 Lyophilized CD40LG HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400020 Transient overexpression lysate of CD40 ligand (CD40LG) (as WB positive control) 100 ug
$436.00
TP723872 Purified recombinant protein of Human CD40 ligand (CD40LG / TNFSF5) 10 ug
$255.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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