Pf4 (NM_019932) Mouse Recombinant Protein

SKU TP723860

Purified recombinant protein of Mouse platelet factor 4 (Pf4 / PF-4)

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse CXCL4, the region of Val30-Ser105, from gene Accession# NM_019932
• Tag: Tag Free
• Predicted MW: 8.2 kDa
• Concentration: lot specific
• Purity: >98%, as determined by Coomassie stained SDS-PAGE
• Buffer: 1 x PBS
• Bioactivity: Mouse CXCL4 inhibits the proliferation of HUVEC cells induced by recombinant human FGF-basic (Cat. No. TP723719). The ED50 for this effect is 0.8 – 4 µg/mL.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_064316
• Locus ID: 56744
• UniProt ID: Q9Z126
• Cytogenetics: 5 E1
• RefSeq Size: 525
• RefSeq ORF: 315
• Synonyms: Cxcl4; Scyb4
• Summary: Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation (By similarity).[UniProtKB/Swiss-Prot Function]