VEGFC (NM_005429) Human Recombinant Protein

CAT#: TP723856

Purified recombinant protein of Human vascular endothelial growth factor C (VEGFC)

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: CHO
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Human VEGF-C, the region of Thr103-Arg227, from gene Accession# NM_005429.2
• Tag: C-His
• Predicted MW: 15.4 kDa
• Concentration: lot specific
• Purity: >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: The ED50 is 100 ~ 500 ng/ml, corresponding to a specific activity of 0.2 - 1.0 x 10^4 units/mg, determined by the dose dependent stimulation of HUVEC cell proliferation.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_005420
• Locus ID: 7424
• UniProt ID: P49767
• Cytogenetics: 4q34.3
• Refseq Size: 2103
• Refseq ORF: 1257
• Synonyms: Flt4-L; LMPH1D; LMPHM4; VRP
• Summary: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma