IL2 (NM_000586) Human Recombinant Protein

CAT#: TP723850

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Purified recombinant protein of Human interleukin 2 (IL2)


 Product Datasheet for 'TP723850'

  View other "IL2" proteins (12)

USD 195.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Human interleukin 2 (IL2)
Species Human
Expression Host Sf9
Tag Tag Free
Predicted MW 15.4 kDa
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity Purity is >95%, as determined by Coomassie stained SDS-PAGE.
Buffer 10mM NaH2PO4, pH7.2, 150mM NaCl.
Bioactivity The ED50 is 0.5 - 2.0 ng/ml, corresponding to a specific activity of 0.5 - 2.0x10^6 units/mg, determined by the dose dependent stimulation of CTLL2 cell proliferation.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Reference Data
RefSeq NP_000577
Locus ID 3558
Refseq Size 822
Cytogenetics 4q27
Refseq ORF 459
Synonyms IL-2; lymphokine; TCGF
Summary The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus

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Other Versions

Frequently bought together (1)
IL2 mouse monoclonal antibody,clone OTI2C9
    • 100 ul

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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