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Igf2 (NM_001122736) Mouse Recombinant Protein

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SKU
TP723848
Purified recombinant protein of Mouse insulin-like growth factor 2 (Igf2), transcript variant 2
Size:
25 ug
  $345.00
5 Days*
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Specifications
Specifications
Product Data
Species Mouse
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Mouse IGF-II, the region of Ala25-Glu91, from gene Accession# NM_001122736.1
Tag Tag Free
Predicted MW 7.4 kDa
Concentration lot specific
Purity >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS
Bioactivity The ED50 is 10 - 30 ng/ml, corresponding to a specific activity of 0.3 - 1 x 10^5 units/mg, determined by the dose dependent stimulation of MCF-7 cell proliferation.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001116208
Locus ID 16002
UniProt ID P09535
Cytogenetics 7 87.99 cM
RefSeq Size 3701
RefSeq ORF 540
Synonyms AL033362; Igf; Igf-; Igf-2; Igf-II; M; M6; M6pr; Mpr; Peg; Peg2
Summary This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. It is an imprinted gene that is expressed only from the paternal allele. The encoded protein undergoes proteolytic processing to generate a mature peptide. The transgenic overexpression of this gene in mice results in prenatal overgrowth, polyhydramnios, fetal and neonatal lethality, disproportionate organ overgrowth including tongue enlargement, and skeletal abnormalities. Mice lacking the encoded protein exhibit growth deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. provided by RefSeq, Oct 2015
Protein Categories Cancer: Endocrine, Cancer: Gastrointestinal, Growth Factors, Membrane Proteins, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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