Epo (NM_007942) Mouse Recombinant Protein

CAT#: TP723842

Purified recombinant protein of Mouse erythropoietin (Epo)

Product images

Specifications

Product Data

• Description: Purified recombinant protein of Mouse erythropoietin (Epo)
• Species: Mouse
• Expression Host: CHO
• Tag: Tag Free
• Predicted MW: 18.6 kDa
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer
• Purity: >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: The ED50 is 0.5 - 2.5 ng/ml, corresponding to a specific activity of 0.4 - 2 x 10^6 units/mg, determined by the dose dependent stimulation of TF-1 cells proliferation.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method

Reference Data

• RefSeq: NP_031968
• Locus ID: 13856
• Refseq Size: 715
• Cytogenetics: 5 76.5 cM
• Refseq ORF: 579
• Summary: This gene encodes the glycoprotein hormone erythropoietin that regulates the production of red blood cells and biosynthesis of hemoglobin. The predominant expression of this gene shifts from the liver during fetal development to kidney in adults. A complete lack of the encoded protein causes embryonic lethal anemia in mice. The conditional inactivation of this gene in adult mice results in a chronic, normocytic and normochromic anemia. Transgenic mice expressing the human ortholog of this gene exhibit polycythemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]