Fgf2 (NM_008006) Mouse Recombinant Protein

SKU TP723774

Purified recombinant protein of Mouse fibroblast growth factor 2 (Fgf2)

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse FGF-basic, the region of Ala11-Ser154, from gene Accession# NM_008006
• Tag: Tag Free
• Predicted MW: 16.2 kDa
• Concentration: lot specific
• Purity: >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 10 mM NaH2PO4, 150 mM NaCl, pH 7.2, 1 mM DTT, 0.5 mM EDTA
• Bioactivity: The ED50 is 0.3 to 2 ng/ml, corresponding to a specific activity of 3.3 to 0.5 x 10^6 units/mg, determined by the dose dependent stimulation of 3T3 cell proliferation.
• Endotoxin: Less than 0.01 ng per ug protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_032032
• Locus ID: 14173
• UniProt ID: P15655
• Cytogenetics: 3 18.41 cM
• RefSeq Size: 695
• RefSeq ORF: 462
• Synonyms: bFGF; Fgf-2; Fgfb
• Summary: Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis.[UniProtKB/Swiss-Prot Function]