Fgf2 (NM_008006) Mouse Recombinant Protein
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | Tag Free |
| Predicted MW | 16.2 kDa |
| Concentration | lot specific |
| Purity | >98%, as determined by Coomassie stained SDS-PAGE. |
| Buffer | 10 mM NaH2PO4, 150 mM NaCl, pH 7.2, 1 mM DTT, 0.5 mM EDTA |
| Bioactivity | The ED50 is 0.3 to 2 ng/ml, corresponding to a specific activity of 3.3 to 0.5 x 10^6 units/mg, determined by the dose dependent stimulation of 3T3 cell proliferation. |
| Endotoxin | Less than 0.01 ng per ug protein as determined by the LAL method |
| Storage | Store at -80°C. |
| Stability | Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_032032 |
| Locus ID | 14173 |
| UniProt ID | P15655 |
| Cytogenetics | 3 18.41 cM |
| RefSeq Size | 695 |
| RefSeq ORF | 462 |
| Synonyms | bFGF; Fgf-2; Fgfb |
| Summary | Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis.UniProtKB/Swiss-Prot Function |
| Protein Categories | Chemokines, Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins |
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