Ccl2 (NM_011333) Mouse Recombinant Protein

CAT#: TP723768

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Purified recombinant protein of Mouse chemokine (C-C motif) ligand 2 (Ccl2 / MCP-1)

  View other "Ccl2" proteins (3)

USD 340.00

2 Weeks

    • 10 ug

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Product Data
Description Purified recombinant protein of Mouse chemokine (C-C motif) ligand 2 (Ccl2 / MCP-1)
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence Mouse MCP1, the region of Gln24-Arg96, from gene Accession# NM_011333
Tag Tag Free
Predicted MW 8.5 kDa
Concentration lot specific
Purity >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS
Bioactivity The ED50 is 8 -15 ng/ml, corresponding to a specific activity of 0.6 - 1.25 x 10^5 units/mg, determined by the dose dependent chemoattraction of THP-1 cells.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Reference Data
RefSeq NP_035463
Locus ID 20296
Refseq Size 806
Cytogenetics 11 49.82 cM
Refseq ORF 447
Synonyms AI323594; HC11; JE; MCAF; MCP-1; MCP1; Scya2; Sigje; SMC-CF
Summary This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. [provided by RefSeq, Sep 2015]


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