Ccl2 (NM_011333) Mouse Recombinant Protein

CAT#: TP723768

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Purified recombinant protein of Mouse chemokine (C-C motif) ligand 2 (Ccl2 / MCP-1)


 Product Datasheet for 'TP723768'

  View other "Ccl2" proteins (4)

USD 265.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Mouse chemokine (C-C motif) ligand 2 (Ccl2 / MCP-1)
Species Mouse
Expression Host HEK293
Tag Tag Free
Predicted MW 8.5 kDa
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS
Bioactivity The ED50 is 8 -15 ng/ml, corresponding to a specific activity of 0.6 - 1.25 x 10^5 units/mg, determined by the dose dependent chemoattraction of THP-1 cells.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Reference Data
RefSeq NP_035463
Locus ID 20296
Refseq Size 806
Refseq ORF 447
Synonyms AI323594; HC11; JE; MCAF; MCP-1; MCP1; Scya2; Sigje; SMC-CF
Summary This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. [provided by RefSeq, Sep 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones
HUMAN PROREINS 101