Il17a (NM_010552) Mouse Recombinant Protein

CAT#: TP723750

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Purified recombinant protein of Mouse interleukin 17A (Il17a)


 Product Datasheet for 'TP723750'

  View other "Il17a" proteins (2)

USD 195.00


Availability*
5 Days

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Mouse interleukin 17A (Il17a)
Species Mouse
Expression Host E. coli
Expression cDNA Clone or AA Sequence Mouse IL-17A, the region of Ala26-Ala158, from gene Accession# NM_010552
Tag Tag Free
Predicted MW 15 kDa
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity Purity is >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 10 mM NaH2PO4, 0.15 M NaCl, pH7.2
Bioactivity The ED50 is 0.25 - 1 ng/ml, corresponding to a specific activity 1.0 - 4 x 10^6 units/mg, determined by a dose dependent stimulation of fetal mouse skin fibroblasts production of IL-6.
Endotoxin Less than 0.01 ng per ug protein as determined by the LAL method.
Reference Data
RefSeq NP_034682
Locus ID 16171
Refseq Size 1171
Refseq ORF 477
Synonyms Ctla-8; Ctla8; IL-17; IL-17A; Il17
Summary This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Sep 2015]

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BOGO Free lysates
68 Mouse Clones
HUMAN PROREINS 101