Il1a (NM_010554) Mouse Recombinant Protein

CAT#: TP723741

Purified recombinant protein of Mouse interleukin 1 alpha (Il1a)

Product Images

Specifications

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse IL-1alpha;, the region of Ser115-Ser270, from gene Accession# NM_010554
• Tag: Tag Free
• Predicted MW: 18 kDa
• Concentration: lot specific
• Purity: Purity is >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 10 mM NaH2PO4, 150 mM NaCl, pH 7.2
• Bioactivity: The ED50 is 1- 5 pg/ml, corresponding to a specific activity of 1- 0.2 x 10^9 units/mg, determined by the dose dependent stimulation of D10S cells proliferation
• Endotoxin: Less than 0.01 ng per ug protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_034684
• Locus ID: 16175
• UniProt ID: P01582, Q3U0Y6
• Cytogenetics: 2 62.9 cM
• Refseq Size: 1974
• Refseq ORF: 813
• Synonyms: Il-1a
• Summary: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.[UniProtKB/Swiss-Prot Function]